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Might be referring to: each single-use pre-filled pen contains 300 mg of dupilumab in 2 ml solution (150 mg/ml). Dupilumab is a fully human monoclonal antibody against interleukin (IL)-4 receptor alpha that inhibits IL-4/IL-13 signalling, produced in Chinese Hamster Ovary (CHO) cells by recombinant DNA technology..