Ashwagandha Supplement

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came across a blog post by some guy who tried ashwagandha, shilajit and safed musli for 3 weeks after turning 40. belly fat, stress, low energy, cortisol issues. pretty relatable stuff honestly. what got me wasn't his results though. it was the comments section where people kept saying they tried the same herbs and felt nothing. so i started digging into why the same herb works dramatically for some people and does absolutely nothing for others. and the answer kept coming back to one thing. processing. most ashwagandha on the market is just root powder in a capsule. you swallow it, your body extracts maybe 10-15% of what's useful and the rest passes through. the classical texts never described it this way. ashwagandha was always processed, either through milk, ghee or its own plant medium over multiple cycles. the processing is what makes the compounds bioavailable. without it you're essentially eating expensive dirt. this is called bhavana in classical ayurveda. herb powder repeatedly soaked in a specific liquid medium, dried, soaked again, multiple cycles. concentrates the active compounds in a form the body can actually absorb. time consuming, cannot be done at industrial scale without cutting corners, so almost nobody does it. i started looking for brands that actually follow this and honestly most don't even mention it. the ones that do are usually small, not very well known. found one called jeevrasa. been using their rakshaya for immunity and the difference from generic giloy tulsi capsules was noticeable around week 5-6. they apparently have an ashwagandha tablet coming using the same bhavana process which i'm genuinely curious about because ashwagandha processed this way is supposed to be a completely different experience from the standard root powder everyone sells. anyway the broader point is. if you've tried ashwagandha and felt nothing, you probably tried the wrong version. not the wrong herb. the wrong version of it. the guy in the blog got results. most people don't. processing is probably why. submitted by /u/Helpingotherssurvive to r/Ayurveda [link] [comments]

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i want to preface this by saying i thought i was being smart. i was tracking everything, listening to the right podcasts, buying quality brands. i was not being smart. at my peak i was running creatine, omega-3, vitamin D with K2, magnesium threonate, ashwagandha KSM-66, fadogia agrestis, tongkat ali, zinc at 50mg daily, copper to offset the zinc, lion's mane, a B-complex, and CoQ10. $350/month. i had a whole system. then i got a comprehensive bloodwork panel. not the basic one. a real one. and the results were not what i expected. copper: flagged low. because the zinc at 50mg daily was suppressing it. been taking that dose for months thinking i was supporting testosterone. turns out i was slowly depleting a mineral my body needs for actual enzyme function, immune response, and collagen production. B vitamins: way too high. intracellular, not serum. the kind your doctor doesn't run by default. i had neurological tingling in my hands that i'd been ignoring for weeks. you know what causes that? B6 toxicity. which i had. from supplements i was taking because i thought more was better. the fadogia: i'd been taking it based on essentially one rat study where the rats showed liver toxicity at the human-equivalent dose. i think about that now and feel genuinely stupid. one rat study. daily. for months. so what happened when i dropped everything? i kept creatine (5g, decades of evidence), omega-3 high EPA, vitamin D at 3000 IU with K2 MK-7, and magnesium glycinate before bed. switched from threonate because glycinate works better for me personally and costs half as much. total monthly spend: about $45. i feel better. not a little better. noticeably, clearly, actually better than i did on the $350 stack. the tingling is gone. sleep is deeper. i have actual emotions again (ashwagandha blunting is real and nobody talks about it enough). bloodwork came back clean across the board. i also started doing the boring stuff. 8 hours of sleep non-negotiable. cardio 5x a week. protein at 1g per pound. cut alcohol to basically never. morning sunlight. i know. but the gap between "$350/month stack plus okay habits" and "$45/month basics plus actually dialed lifestyle" is not close. they're not even in the same universe. this sub, and the podcast ecosystem around it, has a way of making you feel like you're always behind. like there's always one more compound. and that feeling is what got me to $350/month with nerve damage and a crashed copper level while thinking i was being optimized. get comprehensive bloodwork. not the basic panel. look at what's HIGH, not just what's low. and maybe be honest with yourself about how many things you're running because you have real data versus because a pod ad made it sound necessary. i've been writing more about this stuff over on my substack linked in my profile, if you're curious to go deeper it's there. anyway. i'm genuinely curious if anyone else has done this. pulled way back and felt better. based on the DMs i get when i mention this in comments i don't think i'm the only one. i think a lot of people in this space are quietly spending a fortune, feeling nothing, and too deep in to admit it. EDIT: if you’re here because you’re researching supplement side effects, bloodwork results, or whether your stack is actually helping, this is the short version of what i learned the hard way: • high dose zinc supplementation (50mg+) can cause copper deficiency, which is linked to anemia, immune dysfunction, and neurological issues like numbness and balance problems • excess vitamin b6 (common in b complex, zma, and multivitamins) can cause peripheral neuropathy, including tingling, burning, or numbness in hands and feet • more supplements does not equal better health. stacking can create imbalances, toxicity, and unintended interactions • bloodwork should include intracellular vitamins and minerals, not just standard panels • many popular testosterone boosters (like fadogia agrestis) have limited human evidence and potential safety concerns what actually worked better for me: • minimal, evidence based stack (creatine, omega 3, vitamin d + k2, magnesium) • prioritizing fundamentals: sleep, diet, exercise, sunlight, and alcohol reduction • regular bloodwork to guide decisions instead of guessing if you’re currently taking multiple supplements and not feeling better, or feeling worse, it may be worth asking: “do i actually need this, or am i just optimizing blindly?” submitted by /u/Timely_Ad8989 to r/Biohackers [link] [comments]

submitted by /u/_Aspagurr_ to r/Supplements [link] [comments]

Just a random, curious question that came to me right now as I'm walking on an incline treadmill. submitted by /u/_Aspagurr_ to r/workout [link] [comments]

Hit my 30s and feel like my body just gave up. Work stress, gym recovery takes forever, sleep is trash. Wake up tired, drag myself through the day, can't focus. Used to bounce back in my 20s. Now one bad night ruins the whole week. Tried cutting alcohol. Better sleep helps but stress still there. Cortisol through the roof probably. Buddy recommended ashwagandha. Said it helps with the "wired but tired" feeling. Been trying these ones for a month - gummies with ashwagandha, L-theanine, and magnesium. Not a magic pill but definitely takes the edge off. Sleep feels deeper. Less brain fog. Still figuring it out though. What's your go-to for keeping it together? Supplements? Therapy? Just raw dogging life? Curious what actually works for guys here. Use code GUMMYRED30 if you wanna check out the ones I'm using. submitted by /u/Chrelled to r/AskMen [link] [comments]

So I've been taking Nutricost KSM-66 Ashwagandha root extract for a while now. I ended up pouring 3-4 out and noticed this one that was smaller and white. WTF lol submitted by /u/CoolCatNTopDawg to r/mildyinteresting [link] [comments]

21M here. Had bad social anxiety, shyness, low self-esteem. Someone said Ashwagandha (Carbamide Forte 500 mg) would help with stress & confidence. Started 500 mg daily, sometimes 1000 mg. Took it straight for ~4 months. Then disaster. Severe fatigue → constant heartburn → whole-body itching so bad I scratched feet, scalp, hands until I had open wounds & scars. Skin underneath was yellow. Jaundice hit hard. Bilirubin went to ~50 mg/dL (normal submitted by

submitted by /u/cheaslesjinned to r/NooTopics [link] [comments]

Hi I am an MBBS student from a medical college in India. I am going to address few issues about Ayurveda quackery that is one of the biggest concern right now in Indian healthcare , Please read it fully so that my efforts won't be wasted. (Scroll down if you just want to learn about Side effects of Ayurveda ) First lets start with a few basic definitions that we are going to need later in this post. Modern medicine = It is evidence based medicine that works on scientific principles and is based totally on research and trials. It is evolving continuously and it is the best way of treatment at the present time. BAMS = THESE QUACKS PRESCRIBE AYURVEDIC MEDICINE BHMS = THESE QUACKS GIVE SUGAR PILLS Since I already posted and proved why homeopathy and ayurveda are pseudoscience , if you didn't read original post please read it here https://www.reddit.com/r/india/s/Zf2aeion3k After reading comments I am convinced that around 90% of people are convinced that Homeopathy (BHMS) is indeed a PSEUDOSCIENCE. Now I agree that I cant change those 10%. Now lets move on to ayurveda and after reading comments I found a trend that almost 60 to 70% of people started talking shit about science defending ayurveda while 20% of them are saying both ayurveda and modern medicine (that you guys call allopathy) are good. Sometimes they take ayurveda sometimes modern medicine (allopathy). One of the common reasons I saw is they said ayurveda is good for minor issues and I think they are partially correct. For minor issues ayurveda can work as complementary medicine RIGHT ? Lets study another definition here Complementary medicine = Complementary medicine means treatments used along with modern medical treatment such as yoga or acupuncture used together with prescribed medicines. Now lets see what are the scientifically proven complementary medicines available under Ayurveda Yoga Meditation Pranayama breathing Balanced diet with vegetables fruits whole grains Stress reduction and good sleep routine Now biggest question CAN A MODERN MEDICINE DOCTOR prescribe it?? A BIG YES Why can a modern medicine doctor prescribe it ? Its ayurveda bro!! They can prescribe it because these things are general health practices. Why ayurveda quacks use these few Ayurveda health practices as their base to advertise their pseudoscience?? Because these practices already work for health improvement so ayurveda quacks use them to look scientific and trustworthy then they add unproven treatments to make money. Few of them commented about their INDIVIDUAL EXPERIENCE like my friend got healthy after taking ayurveda he didnt get healthy before by modern medicine WHYYY?? Many illnesses improve with time lifestyle change and placebo effect. Ayurveda may be taken during that natural improvement so people think it caused the cure but it actually did not. Someone said MEDICINE is very costly in India thats why most people go to these quackery medicines. I wanted to address this issue. First drugs in India are the CHEAPEST in the world https://timesofindia.indiatimes.com/india/indian-drug-prices-among-the-cheapest-in-the-world/articleshow/72196203.cms Second Indians pay about 70% less than the global average for modern medicine https://theprint.in/health/indians-pay-70-less-than-the-global-median-to-buy-medicines-study-finds/323856/ But its STILL COSTLY and I completely agree with everyone. Now what I dont agree with here is people blame hospital staff for that costliness. I agree a few of them are indeed but mostly they are genuine because they need to pay Doctors Nurses hospital staff. They need to BUY equipment which is very very costly and mostly imported from other countries so that cost is genuine. WHAT IS THE REAL SOLUTION FOR POOR PEOPLE THEN That is where the role of government comes. Government needs to improve healthcare infrastructure and subsidize it instead of giving freebies like "LADLI BEHEN YOJNA" or "FREE ME PAISE DENA". That is very unfortunate. Someone in comments mentioned BIG PHARMA SCAMS Those who dont know about it let me give you a short explanation about it. Basically what has been happening in recent years is big pharma companies specifically in the United States are organizing clinical trials of drugs specifically in the best population. Read this article to know more about it https://pmc.ncbi.nlm.nih.gov/articles/PMC4046551/ Now lets address this issue. First I completely acknowledge this issue and it is completely illegal and thats why we need urgent medical reforms including clinical trials and regulation of pharma companies. Someone said in comments they take mostly Modern medicine but only use ayurveda in minor cases because it doesnt have any side effects Lets discuss this. Ayurveda indeed has very bad side effects and can lead to damage of your organs. SIDE EFFECTS OF AYURVEDA (Before talking about side effects of Ayurveda I completely acknowledge that Modern medicine has side effects too but the problem arises when it is not acknowledged by you and the general public. Please acknowledge it and try to correct it like in modern medicine we openly talk about side effects) I dont want to state just facts here so I attached research papers justifying the side effects here Ashwagandha (Withania somnifera) Common side effects when taken orally may include stomach upset diarrhea vomiting nausea and headache. Rare but serious risk liver injury or liver failure especially with long term or high dose use https://www.webmd.com/vitamins/ai/ingredientmono-953/ashwagandha?utm_ Tinospora cordifolia (Giloy / Guduchi) There are reports of herb induced liver injury potentially leading to severe liver damage even with standard use. Risky in pregnancy breastfeeding people with chronic illness or liver disease https://en.wikipedia.org/wiki/Tinospora_cordifolia?utm_ (Read toxicology part) Triphala Overuse or high doses may cause digestive discomfort such as abdominal pain or diarrhea https://www.punarjanayurveda.com/blog/do-ayurveda-medicines-have-side-effects/?utm_ Guggul (Commiphora mukul resin) Nausea vomiting belching stomach upset loose stools headaches can occur in some people CHYAWANPRASH Possible liver stress or over stimulation of immune system with heavy or long term use suggesting even natural supplements may not be risk free https://timesofindia.indiatimes.com/life-style/food-news/chyavanprash-dangers-exposed-by-hepatologist-potential-links-to-cancer-and-liver-issues/articleshow/124285980.cms?utm_ FOR COWS Urine I totally support all religious BELIEVE around it and I dont have any problem with it as I respect all religions but when it comes to using it as medicine that is where the problem arises. It carries harmful bacteria and sometimes toxic metals and has no proven medical benefit which means the risks are real and the benefit is not demonstrated https://pmc.ncbi.nlm.nih.gov/articles/PMC8079447/?utm_ https://timesofindia.indiatimes.com/city/bareilly/cow-urine-unfit-for-humans-says-top-animal-research-body/articleshow/99391858.cms?utm_ Read these comments https://www.reddit.com/r/india/s/kmwHdOA1aB https://www.reddit.com/r/india/s/WRsCQFQ0zv https://www.reddit.com/r/india/s/BDody2elIy If you made it till here Thanks for reading my post and believing in Science submitted by /u/Boring_Researcher803 to r/india [link] [comments]

edit: I read this post and ended up buying Alpha core 8 in 1 and i've already noticed a huge difference in how I feel! https://www.reddit.com/r/PeterAttia/comments/1ldu92d/best_ashwagandha_brands/ I've heard Dr. Attia talking a lot about ashwagandha, and I kinda want to try it. The only thing that's stopping me is i'm a little bit confused on what type to get and which brand may be the most reputable? There's a ton of b.s. posted online and I don't want to get the wrong thing or waste my money. Anybody have any suggestions? submitted by /u/Miserable-Coffee-138 to r/PeterAttia [link] [comments]

ashwagandha has been coming up a lot in this sub lately. but i’ve seen that everytime the same handful of brands get thrown around. some actually hold up when you look at the community feedback over time. others… not so much. figured i’d leave a tier breakdown here. ok so i’ll base the tier list on what’s been popping up and how transparent the labels are. * tier 1: people like and prefer it * tier 2: people give these a chance * tier 3: people mostly avoid it we’ll start with the ones to avoid Tier 3: mehh this is where most of the generic store brands and amazon’s choice picks are. spring valley is an example. It has low dose per cap, no standardization info and mostly just raw root powder. nature’s bounty is another. similar story. works on paper but you really don’t know the potency you’re getting. then you’ve got the no name amazon brands like nutrachamps that mix ashwagandha with random fillers. they’re cheap and they’re everywhere. but they’re inconsistent. Tier 2: solid but not standout these ones are fine if you want something simple and reasonably well made. but there are tradeoffs. organic india is clean and organic… but the per-c ap dose is on the light side so you usually need more than one to match clinical ranges. hum calm gummies are an easy sell for people who hate pills. taste is good. but potency isn’t high so effects can be slower or milder. himalaya organic ashwagandha’s is stocked in a lot of stores. decent quality, just not as concentrated as standardized extract formulas. and feedback is more mild mood support Tier 1: the repeat buys these brands keep coming up in threads. myprotein ksm-66 is probably the most mentioned. cos it’s straightforward standardized extract, decent price (nothing extra thrown in). gaia herbs root capsules are another staple. good dose, organic, verified for purity. you’ll see them mentioned in stress and sleep discussions a lot. then there’s nootropics depot’s sensoril. different extract type, higher withanolide content .plus they publish their testing. these are the ones people tend to stick with once they’ve tried a few others. General observations * raw root powder can still work. but at gram level doses and with more patience. * side effects are possible like low energy, stomach upset, libido changes (happens more with higher doses or if you take it earlier in the day). * don’t go for max potency blends with no extraction details. usually not worth it. EDIT: Thank you for the helpful suggestions, I decided to get this onehttps://www.amazon.com/dp/B073DN2YG9 submitted by /u/A1300R to r/Supplements [link] [comments]

Got into the whole health optimization thing after new years, following biohacking influencers and fitness people posting their supplement routines. Started simple with vitamin D cause I work remotely. Then magnesium, ashwagandha for stress, zinc, pre-workout, and some herbal focus thing from amazon. Ended up taking like 8 different things twice a day. By August my stomach was completely screwed. I started getting heartburn at first then it continue to bloating, cramps, exhaustion even though I was "doing everything right." Thought maybe it was food intolerance or something. Finally saw my doctor last week and she checked everything and told me I'd been poisoning myself. Had to stop everything. My gut is wrecked now and I need probiotics to fix it. Wasted $400 over six months thinking I was being healthy. Don't mix random supplements without talking to a doctor first. Learn from my dumbass mistake. TL;DR: Mixed around 7 supplements for the past months not being aware of what I was putting in my body, destroyed my gut and wasted $400. Zinc blocked copper, bad interactions, sketchy Amazon stuff. Always check with doctors first." submitted by /u/LividLawfulness4962 to r/tifu [link] [comments]

Hello everyone! I've been taking ashwagandha for anxiety for a while and it's been great. I take a week or two off it every 30 days because I heard of bad experiences of taking it over 90 days. I think this cycle works great but during those weeks I'm off I do have a rise in anxiety and insomnia. Not always to panic attack levels but sometimes I do. I tried taking it for longer but then after 30 days or so I don't really feel the effects anymore. I walk 3-4 miles every day, taking a few break days here and there, and do self care to manage my stress as well but sometimes my anxiety disorder just acts up for no reason or over reacts to stress. Have been trying to quit nicotine (vaping) as well. submitted by /u/dotdedo to r/Supplements [link] [comments]

I’ve been researching Ashwagandha lately and keep coming across mixed reviews on supplements and their effectiveness for men. Some people say it helps with stress, sleep, and energy, while others mention benefits for strength and testosterone. Since there are so many brands and types (capsules, powders, gummies), I figured Reddit and this subreddit would be the best place to ask real people what’s actually worked for them. What’s the best Ashwagandha supplement you’ve tried, and what kind of benefits did you personally notice? Thanks submitted by /u/netzodus to r/Supplements [link] [comments]

Hi everyone, I'm looking for a supplement that can help lower blood pressure quickly — ideally something that can be felt or measured from the very first day, similar to how Ashwagandha works for stress and anxiety. I’m aware long-term management involves lifestyle changes and possibly medication, but I’m curious about short-term effective supplements that actually produce noticeable effects fast (within hours or a day). Has anyone experienced immediate drops in blood pressure with things like: Magnesium (citrate, glycinate?) L-arginine or beetroot CoQ10 Potassium Omega-3 Or any other that worked fast for you? I’m not on BP meds right now, just tracking it with a home monitor. Any input or personal experience is appreciated! Thanks in advance. submitted by /u/zaico1 to r/Supplements [link] [comments]

Hi everyone, I'm looking for a supplement that can help lower blood pressure quickly — ideally something that can be felt or measured from the very first day, similar to how Ashwagandha works for stress and anxiety. I’m aware long-term management involves lifestyle changes and possibly medication, but I’m curious about short-term effective supplements that actually produce noticeable effects fast (within hours or a day). Has anyone experienced immediate drops in blood pressure with things like: Magnesium (citrate, glycinate?) L-arginine or beetroot CoQ10 Potassium Omega-3 Or any other that worked fast for you? I’m not on BP meds right now, just tracking it with a home monitor. Any input or personal experience is appreciated! Thanks in advance. submitted by /u/zaico1 to r/Biohackers [link] [comments]

3 years ago I was constantly sick so I started a multi vitamin for immune support. I’ve always been a bad sleeper so I also started magnesium and occasionally melatonin. Had some bloodwork and my vitamin D and iron were low so I added that too. Somewhere down the line I got more symptoms then relieve so I tried anything and everything to feel better again. A multi vitamin doesn’t hurt right? And if it’s water soluble there’s no issue, you pee out all the excessive amounts. I’ve also taken l-lysine and selenium for the constant colds and that seemed to help for a long time too. But then out of nowhere I got symptoms like hot flashes, insomnia, excessive thirst and peeing a lot, my hair and skin started to change, neurological symptoms like tingling, stiff neck, even my periods started to change. So I switched it up and took some multi vitamins for hormonal issues instead. Also added ashwagandha because I was starting to get overemotional and stressed out. I went down a rabbit hole where I learned too much zinc is bad for copper, so yup added copper too maybe that was what’s wrong. The symptoms were so bad doctors started to look for CANCER, then thyroid disease but they couldn’t find anything except my igM and neutrophils being off indicating my immune system couldn’t work for me anymore the way it should. Kept pushing the doctor to look at my thyroid again and again because I started to become convinced it’s that. He refused but wouldn’t test my vitamins either. Then I did bloodwork on my own at a third party to see all my vitamin levels and almost everything came back way too high❗️Especially the B vitamins are too high, they suppose to be water soluble (I been told that over and over) but that is where my neurological symptoms, hot flashes, fertility issues and excessive peeing come from. Magnesium is too high which gives me a stiff neck everytime I try to take it and it stole a lot of calcium. Folate is over the top which gives me insomnia for maybe at least 2 months because the test that has been done is intracellular. I’ve been told that some multi vitamins, or any vitamin the formulation can be too high than your body needs and before you know it you’re overdosing, which gives you symptoms. What I’m trying to say is, please do your BLOODWORK FIRST! I learned my lesson that just because it’s “vitamins” it can, and will definitely hurt you when it’s too much and give you symptoms and before you know it you’re spiraling thinking you have a horrible disease but you don’t. I stopped taking everything and feel much better already except for the insomnia, all the hot flashes and excessive sweating/peeing is gone. God I wasted so much money on supplements and they’re all in the bin now, and I also blame this subreddit for it 😂 submitted by /u/Interesting_Name_990 to r/Supplements [link] [comments]

submitted by /u/Coniferous_Needle to r/TheMassive [link] [comments]

I feel so much more focused — last month I completed a solo hike of The Ridgeway, and yesterday I actually managed to make a phone call to book my first session at the ROKTFACE climbing wall! submitted by /u/ForestGoldMiner to r/TwoSentenceHorror [link] [comments]

Yes sometimes people find supplements a wonder. But after my experiences I feel the warnings need to be so much more explicit. I don’t even have the brain capacity to write my full experience right now it’s just like I want to get a warning out there. I have tried all of the above at different times in very small doses and with each I have had a a few amazing experiences but always followed by horrific mental health. I’m incredibly frustrated that lion’s mane, purported to be another wonder herb is the most recent I have tried and it has completely messed up the progress I had made after quitting caffeine and alcohol (which I didn’t have very much of). I just wanted to warn people, Holland and Barrett and other health food and supplement stores really might be harming us. Edit: Please stop telling me I need to do more research, I am AuDHD what do people think my approach has been?! 🙃 this is merely a warning that despite incredible amounts of research and product selection terrible things can still happen. submitted by /u/AnyAliasWillDo22 to r/AuDHDWomen [link] [comments]

I'll try to condense the first part of this and get to the important details, but a little background information is needed to tell the full story. Around May 1st, I started itching from head to toe. I thought that I was having an allergic reaction, so after it didn't subside in a few days, I went to urgent care. At this time, I hadn't noticed that I didn't have a rash, because excessive scratching had broken capillaries and I had mistaken those for hives. They were not. Urgent care gave me steroids and sent me on my way. The itch went away for a week and then returned. No rash, no hives. I went to my PCP, who said it was because my skin was too dry, told me to stop showering daily, and gave me another steroid shot. This steroid shot did not start working immediately. I stepped up my skincare game and the itch finally stopped. Until July. The itching started again. Went back to the PCP. He said that my skin wasn't too dry, maybe it's allergies. Gave me another steroid shot and told me that I needed to figure out what was causing this because I couldn't just keep coming back for steroid shots every other month. Told me to take antihistamines. I requested a complete metabolic panel at the suggestion of a friend who is also a doctor. That was a Tuesday, about three weeks ago. Test came back on Friday morning. Bilirubin, ALT, and AST were all slightly elevated. I sent my PCP a message in the portal asking for next steps. No answer. Called and left a message in the afternoon, no answer. By 5 pm, I was in so much pain. The itch was burning my skin and I had not slept at all the night before. Finally got a hold of him, he said that the test results didn't look concerning to him and to take an antihistamine. I said no antihistamine had worked. I was taking an h1 and h2 blocker. He prescribed a stronger antihistamine. (Yes, I will be finding a new PCP). Did not sleep at all that night and had my husband drive me to the ER the next morning. Total bilirubin was at 2.7 (which was what was causing the itching, normal range is 1.1), ALT was 442 (normal range is below 64), AST was 240. Ultrasound showed no bile duct obstructions and healthy gallbladder (I have a family history of gallbladder disease). I was given cholestyramine to help reduce the bilirubin and referred to a liver specialist. After convincing the Hepatologist that I was not a junkie alcoholic that traveled to exotic locations, he begin asking me other questions. Family history of liver disease - no. How much do you drink - only one drink a night with dinner on Fri, Sat, Sun. Do you take any herbal supplements? - yes. Ashwagandha, Valerian Root, 5-HTP, Turmeric. Was told to stop taking all herbal supplements immediately and begin daily blood tests. Monday's test they took 12 vials of blood, to rule out pretty much everything that could harm your liver. I was bruised for two weeks from that. The itching got better, but my ALT and AST just kept going up and up. I started researching everything that I was taking, which led me to the study that came out of Iceland earlier this year. By Friday, my liver levels were still rising, which was super frustrating, because I was doing everything that they told me to. I was also focusing on eating foods that were supposed to be good for your liver. Which was difficult, because I had absolutely no appetite. The NP said that a lot of times the enzymes will continue to go up, peak, and then start trending down. But, they were worried because my levels were still climbing and the lab was closed during the weekend. I also had zero energy, which also worried them. So, I got to go to the hospital. During COVID. Which I do know I did not have because they stuck the swab up my nose. Let me tell you, you never want to hear: 'you hopefully won't need one, but we want you to go to the hospital where we do liver transplants just in case.' They did mention that my blood results showed my liver was still functioning properly, which was hopeful. They stuck me in an MRI to rule out any obstructions that hadn't shown up on the ultrasound. I had to get my blood drawn every 12 hours to monitor my levels. Saturday, they didn't let me have any food OR WATER until 2 pm when they ruled out doing a biopsy for that day, which gave me the worst headache I've had in my life. Then they didn't get approval from the doctor to give me ibuprofen until almost 10 pm. My AST and ALT levels peaked on Saturday. ALT was 1514 and AST was 572. Every morning, I would have to wait to hear if they wanted do a biopsy that day. Luckily, Monday morning my levels had dropped enough that, not only were they not going to do the biopsy, they were sending me home. So, I was diagnosed with Drug Induced Liver Injury. The liver team said that they had seen previous cases associated with Ashwagandha, Valerian Root, and Turmeric, but didn't pinpoint any of the three as the specific cause. The resident working with the liver team said that when your liver enzyme levels get that high either they peak and trend downward or you go into liver failure. The liver doctor said that they had seen a couple of otherwise healthy people end up needing transplants from supplement use (didn't mention which specific ones) and that I should consider myself lucky. I'm home now and feeling better. I'm only allowed to take my prilosec, the liver meds they gave me, and melatonin. They won't even let me take my birth control until my levels go back to normal. Last Thursday, my bilirubin had gone down to .8 (within normal range!), AST to 90, and ALT to 500. I go back for another blood draw on Thursday. Weekly blood draws are much better than daily (or twice daily). My poor veins had so many holes in them. So, I've been going down the rabbit hole researching every little thing I'd taken the past three months. I found a form that you could submit a report to the FDA if a supplement had caused a serious issue. While filling out the form, I clicked over to Amazon to get the exact name of the Ashwagandha brand I had been taken. Then I noticed it. I purchased it on April 21. Which means it arrived around April 23. A week before the first itching event. Curious, I clicked on the reviews. Almost all of the one and two star reviews mention itching. Several also mention high liver enzymes. Dozens and dozens of reviews. This has to be the culprit. There's too much data here. I've been taking Ashwagandha for a couple years now, but it had been the first time that I had bought the NOW Supplements brand. In the past I had used Organic India, Swanson, and even Spring Valley without issue. My doctor has advised me to no longer take Ashwagandha. Which sucks because it did a great job at calming down my ADHD brain so that I could sleep. But, I thought would be prudent to warn others. You do not want to experience this itch. Trust me. TL;DR - Lots of words to say that I ended up in the hospital with Drug Induced Liver Injury. Evidence points to NOW Supplements brand Ashwagandha as the cause. submitted by /u/skinonfirethrowaway to r/Supplements [link] [comments]