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RE:Spike's Latest Blood Test Report!
... glucose regulation, meaning your body’s insulin sensitivity is reduced. Why it... sleep and chronic stress raise insulin resistance. 2. Cardiovascular Risk Profile Lipids...: – Dietary pattern: Mediterranean or DASH diet—rich in vegetables, fruits, oily ... disease. With focused lifestyle measures—diet, exercise, weight management—and regular...
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forums.hardwarezone.com.sg |
Multiversal |
Apr 30, 2026 |
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RE:amino acids instead of (or possibly in addition to) other supplements?
... to a very clean Mediterranean diet. I only started taking levodopa... safe to add to the diet.  Tryptophan — directly addresses levodopa-induced serotonin ..., and excess valine can worsen insulin resistance. Tyrosine — more nuanced. It’s the ..., and daily supplementation partially counteracted insulin resistance development and the loss in ...
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healthunlocked.com |
PDGurl |
Apr 29, 2026 |
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RE:Ceylon cinnamon or berberine?
... money and focus on your diet and exercise and, if on... eating, whereas Metformin helps with insulin resistance which someone in deep remission...
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forum.diabetes.org.uk |
Marc7 |
Apr 28, 2026 |
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RE:Cruising while on GLP1 meds
... LIFESTYLE change - not a diet. Your palate will change, among... it. They have programs for insulin resistance, high cholesterol, etc. https://lifestylerx....
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boards.cruisecritic.com |
cjpj |
Apr 28, 2026 |
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RE:Metabolomic signatures of extreme old age: findings from the New England Centenarian Study
... rather than replaces, resistance exercise and a protein-replete diet. Novelty This is ... improves glycemic control and insulin sensitivity. Evidence Level: Level B....showing significant reductions in fasting insulin and HOMA-IR (insulin resistance) following 8 weeks of ...supplementation in diabetic populations Taurine supplementation plus low-calorie diet...
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www.rapamycin.news |
RapAdmin |
Apr 28, 2026 |
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What are the ways to lower your blood sugar?
... differing symptoms. Though a proper diet and exercise are always a... often attributed to obesity and diet, although as it was in... people have varying levels of insulin resistance, bombarding the body with sugars ...
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steamcommunity.com |
Leonardo Da Pinchi |
Apr 27, 2026 |
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RE:First trimester & feel like I’m losing control of my food choices which is so unusual for me…
... have insulin resistance so I’ve been on a low carb, animal based diet...
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community.whattoexpect.com |
Alorasb |
Apr 27, 2026 |
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RE:Fight Aging! Newsletter, April 27th 2026
... acidosis-induced derangements include catabolic signaling, insulin resistance, increased inflammatory cytokines, mitochondrial dysfunction... whales' exceptional lifespan and cancer resistance is their superior genome maintenance... for key covariates such as diet, age and activity levels. Key...
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www.longecity.org |
reason |
Apr 26, 2026 |
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RE:LADA 1.5
...a type of Type 1 insulin diagnosed as an adult. ... 2 characteristic which basically means insulin resistance. However, due to the... Your body has decided the insulin producing cells bad and and...is managed through insulin and not diet. Eating a low carb diet can make ...the insulin dosing more complex and can increase insulin resistance. The... if you are experiencing insulin resistance.
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forum.diabetes.org.uk |
helli |
Apr 25, 2026 |
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RE:Unexplained secondary infertility
... like I also have some insulin resistance so ive added inositol to... been monitoring blood sugar with diet and exercise. I’m really hoping...
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community.whattoexpect.com |
nobo92 |
Apr 24, 2026 |
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RE:Primate Lipidomics: Caloric Restriction Decouples Metabolic Aging from Chronological Time
...lipid handling rather than just diet composition, GLP-1 medications primarily ...approx. 30%), unless paired with resistance training and high protein intake... (via the downregulation of insulin/IGF-1 signaling) as a potential ...was the delay of age-related insulin resistance. Insulin Sensitivity: The paper notes that ... pharmacological target of rapamycin. Insulin Sensitivity Variable Highly dose- and ...
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www.rapamycin.news |
RapAdmin |
Apr 24, 2026 |
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RE:The Myth Busting Approach Headline: The Million Dollar Question: Do we all have the same "setting"? ?
... living with debilitating chronic fatigue, insulin resistance, weight I couldn’t lose, chronic... that what helps you is diet and exercise, but they don’t ...
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community.whattoexpect.com |
Bookiejunkie |
Apr 23, 2026 |
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RE:Frosted Died
... is largely hormone related - insulin and cortisol - if there... likely related to their diet. Diet can contribute to insulin resistance and other metabolic disorders...
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forum.chronofhorse.com |
beowulf |
Apr 23, 2026 |
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RE:My Type 2 journey
... produces more effectively by reducing insulin resistance and reduces the release of ... make a small difference but diet can do just as much. ...
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forum.diabetes.org.uk |
Leadinglights |
Apr 23, 2026 |
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RE:Mounjaro Ausschleichen und Erhaltung
...Evidence and Mechanisms of High-Protein Diet induced Weight Loss. Veröffentlicht in...al. Effects of aerobic training, resistance training, or both on glycemic... The Effect of Inactivity on Insulin Sensitivity. Veröffentlicht in Journal of...et al.: 72-hour window of insulin sensitivity. Auch die m.E. ...of a combination of high-protein diet and resistance training... Eine proteinreiche Ernährung kombiniert ...
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www.abnehmen.com |
.Ralf |
Apr 21, 2026 |
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RE:only 15% old ppl are healthy
... Diet: Running on ketones is therapeutic for mitochondria and helps correct insulin resistance... [09:27]. 10. Avoid Snacking: Frequent eating spikes insulin; eat...
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forum.lowyat.net |
TiramisuCoffee |
Apr 21, 2026 |
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RE:So confused by all the different weight loss methods and trends.
... night, and there's mention of insulin resistance being the number one cause ... I'm finding all the different diet options so bewildering. The Keto... diet sounds amazing, especially in combination ... though is that the keto diet advises to consume the massively...
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www.bluelight.org |
LakeGuyNE |
Apr 21, 2026 |
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RE:Digestion times and BG levels
..., it can also lead to insulin resistance. I am not suggesting pizza... 762 VL Carb diet and exercise and metformin, started basal insulin Oct 25...
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forum.diabetes.org.uk |
FlibbityGibbet |
Apr 20, 2026 |
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Re: Aspirin May Fight Cancer But Not for the Reason You Think
... eliminated seed oils from your diet for at least six months... damage your gut lining, spike insulin, and create systemic inflammation. Seed..., or grass fed butter. Beyond diet, look at your movement and... human function. Build muscle through resistance training, because muscle is your... glucose sink that protects against insulin resistance. Track simple, inexpensive markers like...
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bitcointalk.org |
BADecker |
Apr 19, 2026 |
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RE:How would we look differently (evolution for 2025 tasks)
... ability to eat a shitty diet and lead a poor lifestyle..., etc. We evolved traits like insulin resistance, obesity, etc to survive times...
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boards.straightdope.com |
Wesley_Clark |
Apr 19, 2026 |
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RE:BBC - What I learned when I gave up sugar for six weeks
.... 50g for a 2,000-calorie diet). The NHS recommends "free sugars... fat and can lead to insulin resistance and Type 2 Diabetes. Verification... called "Type 3 Diabetes" because insulin resistance in the brain is a ...
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forums.hardwarezone.com.sg |
Not.banned.yet |
Apr 19, 2026 |
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RE:Weight loss advice
... people have some level of insulin resistance and do not realize it... thrive on a low carb diet. I also think some of... making the experience about your diet preferences.
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community.whattoexpect.com |
HumbleBumbleMama |
Apr 18, 2026 |
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RE:Can’t make progress - thoughts?!
... attention) @20sam91; • where is your insulin sensitivity at ? ..what is you... TEST ..CAN impact insulin sensitivity ..& CAN contributing to insulin resistance/blood sugar dysregulation... that TEST dose ..& just diet down to 8-10%/BF ..THEN... your issue (..you will be insulin sensitive ..& ready to grow) .....
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www.professionalmuscle.com |
SOUR DIESEL |
Apr 17, 2026 |
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PCOS + insulin resistance… belly fat won’t budge. what actually worked for you?
I have PCOS and insulin resistance, and honestly my biggest struggle is the belly fat. It just feels like no matter what I do, it does NOT move. I can be consistent with eating better, working out, etc., and it still feels stuck. Super frustrating. I’m starting to think the insulin resistance piece is what I’m not fully understanding, so I wanted to ask a few things: 1. What apps are you using (if any)? For tracking weight, food, symptoms, blood sugar, etc. I’ve seen stuff like MyFitnessPal, Cronometer, and some PCOS-specific apps, but I don’t know what’s actually helpful vs overwhelming—especially with insulin resistance in the mix. 2. What kind of workouts actually helped you? I’ve seen so much mixed advice: weight training + walking low-impact workouts avoiding super intense cardio because of cortisol For those with insulin resistance, what combo made a difference for you (especially with belly fat)? 3. Micronutrients / diet — what should I be focusing on? I feel kind of lost here. Should I prioritize: protein? fiber? iron? something specific for insulin resistance? If you’ve figured out ways to eat that actually helped with insulin resistance + weight loss, I’d love to hear what worked. Also if you’ve been in that spot where your body just feels “stuck,” what finally helped things start moving? Appreciate any insight 🙏 submitted by /u/TorontoRap2019 to r/PCOS [link] [comments]
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reddit.com |
TorontoRap2019 |
Apr 30, 2026 |
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Totally reversed insulin resistance (update)
well I made a post a bit back showing my acanthosis nigricans update about a year ago. since then I have reached my goal weight. I have lost over 140 pounds and my neck is completely normal now and the skin tags fell off themselves. my fasting insulin level went from 130 pmol to 40 I ate carbs. carbs weren't the enemy your lack of excerise is. VITAMIN D I WAS SEVERELY DEFICIENT aTE 50K IU EVERYDAY AND THIS BAISICALLY FIXED Y LINGERING ACANTHOSIS. submitted by /u/AncientComb2610 to r/InsulinResistance [link] [comments]
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reddit.com |
AncientComb2610 |
Apr 12, 2026 |
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Can Mounjaro fix something like insulin resistance? Why do I only lose weight easily on it?
I’ve been dealing with something confusing for years and wanted to see if anyone here has experienced something similar. For context, I’ve struggled with fat loss for about 7 years. When I diet without Mounjaro, even on pretty low calories, I lose weight very slowly or sometimes barely at all. It’s been really frustrating and inconsistent. But when I’m on Mounjaro it feels completely different. I can eat 2–3 meals a day (not even extremely strict dieting), and I still lose weight steadily similar to how I used to when I was around 18, when fat loss felt much easier and more normal submitted by /u/ImpressiveSky5365 to r/Mounjaro [link] [comments]
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reddit.com |
ImpressiveSky5365 |
Mar 24, 2026 |
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7 things that actually helped me lose 80 lbs after being diagnosed with insulin resistance
I got a wake-up call about 15 years ago. Elevated fasting insulin, fasting glucose creeping up, A1c heading toward pre-diabetes territory. My doctor told me to eat less and exercise more. I tried that for years and it didn't work. What eventually worked was understanding that the problem wasn't calories, it was insulin. Once I started working with that instead of against it, the weight came off and stayed off. A few things that made the biggest difference: Food order sounds almost too simple but it's real. Vegetables first, protein and fat second, carbs last. The fiber creates a barrier in your digestive tract that slows glucose absorption. Research suggests it can reduce the blood sugar spike from a meal by up to 73%. Same foods, different sequence. Intermittent fasting not as a crash diet but as metabolic rest. Giving your insulin levels time to drop between meals changes how your body accesses stored fat. Cutting ultra-processed food, not because of calories but because of what it does to insulin signaling over time. Happy to answer questions in the comments. submitted by /u/insulinaware to r/InsulinResistance [link] [comments]
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reddit.com |
insulinaware |
Mar 21, 2026 |
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How to lose weight with insulin resistance??
Your body always wants sugar and carbs and your body signals are way off . Every meal needs sweetness Every day your body is in a war Your body doesn’t know what weight to lose with all the sugar in your blood . Please help me submitted by /u/bratz-lady to r/WeightLossAdvice [link] [comments]
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reddit.com |
bratz-lady |
Feb 27, 2026 |
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My whole life I've been put on diets because I was a fat child and I was sure uni would be my chance to finally eat how I want, whatever I want, whenever I want. Got diagnosed with with insulin resistance and my diet has been reduced to cottage cheese, courgette and spinach. Hot water
submitted by /u/bonesideacc to r/kitchencels [link] [comments]
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reddit.com |
bonesideacc |
Feb 23, 2026 |
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We should stop telling people they need GLP-1s for life - insulin resistance is reversible for MOST people (Actually read before you blast me)
I’m getting really tired of seeing comments where people act like insulin resistance is some permanent condition and you’re stuck on semaglutide/tirzepatide forever. For the vast majority of people, this just isn’t true. I’m not fat shaming anyone, and I use this tool as well. I have been obese. I had insulin Resistance. I was pre-diabetic. I have ADHD which makes forming healthy habits a biznitch! I understand that the food industry today makes making healthier choices a nightmare. Look, if you WANT to stay on GLP-1s long-term or even for life, that’s completely fine. It’s your body, your choice, and these drugs are safe enough for that. But what bothers me is people acting like there’s NO OTHER OPTION and you HAVE to be on them forever. That’s just not accurate. The people who genuinely can’t reverse insulin resistance are pretty rare. We’re talking genetic conditions like lipodystrophy or insulin receptor mutations (less than 1% of cases), severe beta cell burnout after 20+ years of uncontrolled diabetes, people on medications they can’t stop like long-term steroids, or major organ damage like cirrhosis. Maybe 5-10% of all insulin resistance cases total. Probably less. The DiRECT trial followed Type 2 diabetics doing just weight loss - no surgery, no GLP-1s. 46% hit remission at 2 years. But here’s the key part: of the people who lost 15kg or more, 86% achieved remission (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)33102-1/fulltext). Bariatric surgery studies show 60-80% remission rates in the first year (https://www.nejm.org/doi/full/10.1056/NEJMoa1600869). Virta Health’s keto program got 53% into diabetes reversal at 2 years (https://www.frontiersin.org/articles/10.3389/fendo.2019.00348/full). Insulin resistance isn’t some genetic death sentence for most people. It develops because you’ve got too much visceral fat, your mitochondria are toast from years of metabolic overload, chronic inflammation, and your cells adapted to high insulin by becoming resistant. Lose significant weight, build muscle, fix your diet, train consistently - these mechanisms reverse. DONT get me wrong - GLP-1s are INCREDIBLE!. They make fat loss way easier, improve insulin sensitivity, reduce inflammation. But they work best as a bridge, not necessarily a forever solution (though again, staying on them is totally valid if that’s what you choose). The problem is people lose 50lbs on a GLP-1, then stop without building any foundation - no muscle mass, no sustainable eating habits, no proper taper. Of course they regain. That’s not proof they need the drug forever, that’s proof they didn’t prepare for maintenance. Type 2 diabetes is only “progressive and irreversible” when you keep doing the stuff that caused it while managing symptoms with meds. When you address the root cause - the excess fat, lack of muscle, the diet - it goes backwards. The reason most people don’t reverse their insulin resistance isn’t because they can’t. It’s because losing 15+ kg and keeping it off is hard as hell. But hard doesn’t mean impossible. If 86% of people can reverse Type 2 diabetes by losing 15kg without any fancy drugs, then convincing yourself you’re stuck on GLP-1s for life (when you don’t want to be) is probably fear of the hard work. Unless you’re in that small group with actual irreversible damage, your body will fix itself if you give it the right conditions. Use the GLP-1 to get the weight off. But also lift weights to build muscle, dial in your nutrition so you’re not relying on appetite suppression, and taper properly. Then you can make an informed choice about whether to stay on or come off - instead of thinking you have no choice at all. You’re not broken. You just might be convinced you are. submitted by /u/Desper84Inspir8ion to r/GLP1ResearchTalk [link] [comments]
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reddit.com |
Desper84Inspir8ion |
Jan 22, 2026 |
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What helped you fix insulin resistance?
I’m 28 male. 6ft 210lbs Recently got blood work done. Homa-IR = 3.71 Fasting insulin = 16 A1c has been at 5.7 for the last year. Fasting glucose = 94 I believe the insulin resistance is also cause high cholesterol. I’ve been on and off with 16:8 intermittent fasting since August. been going for December so far. Completely change my diet. No dairy, high protein from chicken or turkey. Keep carbs at 100g a day or lower. Usually rice, potatoes or tortillas. On a calorie deficit. I got to the gym 3-5 times a week and do heavy lifting Just started fish oil. Also just started with more fiber. Been taking vitamin D everyday. I haven’t seen a doctor yet as they’re either gonna tell me to continue my diet and check in 3 months(which I prefer) or start metformin and statins for the cholesterol. What has helped everyone else lower their levels? submitted by /u/ecase22 to r/InsulinResistance [link] [comments]
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reddit.com |
ecase22 |
Dec 19, 2025 |
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Many women don’t realise how closely PCOS and insulin resistance are connected.
Insulin resistance is actually one of the main underlying causes of PCOS in many women. When your body doesn’t respond properly to insulin, it leads to higher insulin levels in the blood. These excess insulin levels can increase the production of male hormones (androgens), which then disrupt your hormonal balance. This imbalance can cause irregular periods, acne, weight gain around the abdomen, hair thinning, and even worsen PCOS symptoms. The good part is that once insulin resistance is identified and managed through lifestyle changes like balanced diet, regular exercise, better sleep, and reduced stress, PCOS becomes much easier to treat and control. submitted by /u/AskZealousideal6615 to r/PCOS [link] [comments]
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reddit.com |
AskZealousideal6615 |
Oct 31, 2025 |
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What’s the smallest habit that helped your insulin resistance the most?
For those who started improving insulin sensitivity through diet and movement, what tiny change made the biggest difference? Not the big overhauls — I’m talking about subtle daily tweaks that stuck. submitted by /u/Canadian_Insulin to r/InsulinResistance [link] [comments]
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reddit.com |
Canadian_Insulin |
Oct 13, 2025 |
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I got diagnosed with Insulin Resistance and I’m the only one who thinks it’s great news
I had always been relatively lean and while not buff, I was still a decently strong enough woman. Until COVID kicked my ass in 2021 and revealed a whole slew of health issues that were always there but not a huge issue until I got sick. Anyways, I got put on a bunch of different meds in 2022 and by 2023 I had gained about 60 pounds, 70 pounds more than my ideal weight. Sure, my diet wasn’t perfect but it wasn’t so different from what I normally ate. I’ve ALWAYS been one to watch my weight. Also, during this year I was walking each of my dogs separately several times a day, so I was walking an absolute minimum 2-3 miles in intentional walks. Which isn’t crazy, but I have mobility issues so this was still a lot for me. I was also swimming, and have been going to physical therapy for years. I tried cutting calories and tracking again (I do accurately track so this was never an issue), and even at 1200 calories a day for at least 5 days a week for weeks I didn’t lose any weight. Being active isn’t as easy for me anymore with my health conditions and obviously the extra weight. Flash forward now two years later, and I’ve still been trying to lose weight of course I never stopped, but I haven’t seen much results. 10-15 lbs down but that’s it. Obviously, this is super frustrating because I had ALWAYS been able to drop weight easily by just following a deficit. After I had my son 9 years ago, I went down from 140 to 120 in just a few months time easily like no sweat. I haven’t been able to understand what is going on. A year ago I had bloodwork done at my request but only my hormones were checked for the source of my weight gain. They came back mostly normal and this was ruled out. I’m seeing a new provider now and she ran more bloodwork for me but actually checked my insulin and glucose along with vitamin d, calcium, and my hormones. Turns out, I have insulin resistance! Normal A1C, but my glucose and my insulin are high. She explained that this is why I am not seeing results, because my body isn’t equipped to let the weight go at the present moment. She believes it’s mainly the Depo Provera I’ve been on for 7 years! Apparently, that’s too long and it likely damaged my bodies ability to process glucose. So I’ll have to see my gynecologist and find a new birth control method, but the best news is that I’ve started Metformin. It seems like I’m the only one psyched about the diagnosis, because I finally have answers as to why, and I finally have the tools I need to drop the weight. The meds, combined with a lower carb, higher fiber diet should help me finally lose this weight and I really feel elated. submitted by /u/rhaphiloflora to r/loseit [link] [comments]
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reddit.com |
rhaphiloflora |
Aug 24, 2025 |
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My top 10 takeaways from Rhonda Patrick's new episode with Dr. Ben Bikman about insulin resistance
What's up boys. Rhonda just dropped a new episode. Absolute masterclass with Dr. Ben Bikman (insulin resistance expert). All about improving metabolic health. My takeaways below. Here's the episode: https://www.youtube.com/watch?v=gMyosH19G24 Ok... so the absolute worst thing you can do for your sleep: eating sugary food late at night. I think more people do this than they'd like to admit. It basically raises your body temperature and triggers anxiety-like symptoms (that causes insomnia). Give it ~3 hours before bed. No more food after that. (timestamp) You can be insulin resistant with normal glucose levels (This was a MAJOR takeaway from the episode. And insulin resistance is behind so many chronic disease. It's not something to ignore) (timestamp) You tell if you're insulin resistant without a blood test. Two ways. First, check your skin. Look for Acanthosis nigricans (dark, rough neck skin) and small mushroom-like skin tags... both of those indicate insulin resistance. Another thing to check (if you have access to a continuous glucose monitor): After eating a high-carb meal, your blood glucose should return to normal in 2 hours. If it takes longer, that's a problem. (timestamp) High-dose GLP-1 drugs may more than double the risk of blindness, suicidal behavior, and major depression. He cites several studies. Listen, these weight loss drugs are far from perfect. They definitely work as far as helping people lose weight. But so much more research is needed. As of right now... the best use case seems to be: low-dose for short-term (90 days) solely to rewire eating habits (basically, get rid of cravings). Then, after that, revaluate. (timestamp) Early animal studies show vaping impairs mitochondrial oxygen metabolism more severely than traditional cigarettes. Yeah. Crazy right? Vaping worse for mitochondria than smoking. (timestamp) ok.. I always thought the whole apple cider vinegar thing was just a fad. But apparently it works for reducing blood sugar spikes. Just takes a few tablespoons before a meal. Works by inhibiting liver glucose production and activating muscle glucose uptake via AMPK. Berberine is also a fantastic supplement for improving glucose control. (timestamp) There's this great segment about "hidden causes of weight gain". For example, statins -- they increase diabetes risk by ~50% in middle-aged women (cholesterol-lowering drugs disrupt mitochondria, raising metabolic disease risks). Similar with antipsychotics and antidepressants, they also promote weight gain. (timestamp) Exposure to air pollution (especially diesel exhaust and cigarette smoke) promotes insulin resistance and significant fat gain independent of diet. So air pollution can actually facilitate weight gain. Get a HEPA filter if you can, especially if you live in a big city. (timestamp) Easy one here. But so many people do it. The best thing you can do for metabolic health? Not eat a sugary breakfast. You might laugh, but like 90% of Americans eat pastries, doughnuts, cereal for breakfast. (timestamp) 90 days is enough time to reverse insulin resistance. It takes work. But you can do it. Control carbs, prioritize protein, and exercise. Full protocol here: timestamp Her show notes also have a very detailed episode summary, that's where I got a lot of this. oh, also some blood markers discussed: Fasting Insulin: Below 6 µU/mL is optimal; levels above 15 µU/mL suggest insulin resistance. Triglyceride-to-HDL Ratio: A ratio under 1.5 indicates healthy lipid balance Uric Acid: Lower levels are best submitted by /u/biohacker045 to r/Biohackers [link] [comments]
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reddit.com |
biohacker045 |
Jul 15, 2025 |
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How I reversed insulin resistance in 6–8 months
I’m sharing my personal experience in case it helps others here. About 8 months ago, I had multiple symptoms of insulin resistance: constant fatigue, belly fat that wouldn’t go away, high fasting insulin, mood swings, sugar cravings, and even skin tags. My labs confirmed it. I felt frustrated and honestly quite hopeless at times. I decided to go all-in on understanding how my metabolism works. What helped me the most was: Time-restricted eating (I used a 16:8 window almost daily) Low-carb, whole-food diet (not strict keto — I still included lots of cruciferous and colorful vegetables) Short daily walks after meals + resistance training 3x/week Sleep, stress regulation, and supporting my gut (including L. Reuteri) Reducing liver fat through consistent habits After 6–8 months, I lost 40+ kg (~90 lbs), stabilized my mood and energy, and my fasting insulin normalized. I feel more mentally clear than ever before. I recently wrote a book where I describe everything in detail — no protocols or supplements promoted, just a personal journey. If you’re curious, I can share more via DM. Happy to answer questions or hear what worked for you too. This is not medical advice, just my own path. submitted by /u/your-price-booking to r/InsulinResistance [link] [comments]
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reddit.com |
your-price-booking |
Jun 19, 2025 |
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I lost almost 80lbs without GLP-1s; insulin resistant, addicted to sugar. Here’s how.
This is meant to be encouraging for those who cannot take GLP-1s for whatever reason, financial or medically. Full disclosure: I discovered I have ADHD pretty strongly, once I started medication for ADHD, I noticed I wasn’t instantly overwhelmed with the thought of preparing food, nor was I as driven to eat purely out of dopamine rushes. If you have ADHD as well as PCOS, I recommend looking into treatment. Supplements used: Spearmint tea every night (for facial hair growth) Coq10 A good multivitamin Vit D+K Magnesium Glycenate Inositol (I used theralogix) twice daily Berberine (although i don’t think it helped me) Tactics: I implemented intermittent fasting and I truly believe it helped my insulin resistance. If the thought of IF feels overwhelming, try making your dinner be the last thing you eat for the evening, and just break your fast in the morning. 30g of protein for breakfast at least. I never woke up hungry, and found out it was a sign of high cortisol. Because I couldn’t stomach food in the morning, I opted for a keto protein shake (Isopure), plus a scoop of collagen and Benefiber. It gave me protein without feeling like I was eating. Then I had my coffee. Having coffee first always set me up for making poor choices in my day, it’s best to have protein beforehand. Lunch: I noticed if I grabbed a snack plate for lunch, it helped me with the daunting task of figuring out a balanced meal. Grabbing a handful of cherry tomatoes, cucumbers, leftover chicken, crackers etc. Dinner: I allowed myself to be creative, if you’re addicted to food like I am, the idea of a “diet” is low dopamine. But if I planned a new meal I’ve never attempted, I was excited to be in the kitchen. I didn’t eliminate potatoes or rice, just lowered the portion size of my serving and upped the protein. For example, chicken curry with rice (less rice, more chicken). Most importantly, I lowered my calories. If you do all the right things, but are still eating in a caloric surplus, you will not lose weight. I highly recommend the “Lose It” app. If that’s too much for you, which it was for me at times, just having a general idea to eat less on your plate that you used to is a good start. Don’t deny yourself or starve yourself. Exercise: I worked out ZERO before this journey. I started with 10 min videos of Pilates on YouTube. Very slowly upped it to 20 minute videos. Incorporated some dumbbells, but overall I didn’t over exert myself, and didn’t want to burn myself out. Some truths: Yes, I ate a small treat at the end of the night. I was careful though. A serving of M&Ms, (seriously, check the serving size) or a s’more, or a cookie (one!). If I denied myself of any joy from this, I wouldn’t have done it. I viewed it as a change of lifestyle, not a hardcore diet. I still drink coffee with milk and cream in it. It was another non negotiable for me. I tried the dairy free nut creamers and it tasted like garbage. Life is supposed to bring bits of happiness and if I can’t have my damn coffee with cream then forget it. Be patient. It took me a full year to lose about 50lbs, working very hard at it everyday. I’m currently losing my last 10lbs before my ultimate goal weight and it’s been 2 years of this journey. Periods: weight loss alone wasn’t enough to give me back my period, that’s ok, my pcos was super bad! I took progesterone supplements from my endocrinologist to induce a period for 3 months before it tricked my body into creating one on its own. I’ve had a normal 28-30 day cycle now for 1.5 years. I don’t think I could have done this without treating my ADHD first. The thought of creating a meal for myself was overwhelming. I ate out for almost every meal and I was absolutely miserable. There IS light at the end of the tunnel. You aren’t immune to weight loss, there is hope. My skin cleared up from the cystic acne I was getting, my energy is up, my mood is better, I feel better. I hope you know, I really thought I was going to be doomed forever. If I can do it, you can too. submitted by /u/speshyy to r/PCOS [link] [comments]
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reddit.com |
speshyy |
Apr 24, 2025 |
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GLP-1 Insulin Resistance Rant
Any feedback, advice, shared experience welcome I am so sick of pretending this doesn’t bother me. Tirzepatide. Semaglutide. GLP-1 medications. They were never intended to be diet culture trends. They were created to treat real medical conditions. Diabetes. PCOS. Insulin resistance. Metabolic dysfunction. They were designed to save lives. To manage broken hormonal systems. To give people like me a real chance at health when nothing else worked. Through all my research analyzing studies on Google Scholar, I have found that this medication was first studied for its effects on insulin, blood sugar, and hormone production. It was discovered that weight loss is a secondary side effect of those corrections being made. Weight loss was never the goal. It was never supposed to be the treatment itself. The treatment was for the disease. For the dysfunction. For the parts of our bodies that medicine has ignored for decades because it was easier to just blame us. Now I see the same people who never had to fight for their health. The same people who never had to endure fatphobia in a doctor’s office. The same people who have no idea what it feels like to be dismissed over and over again. They are flooding the internet with “If you’re mad I’m taking it, oh well.” Like it is just some fun little trend they stumbled into. Like they are entitled to it. They are driving up the costs. They are creating shortages. They are making it harder and harder for people like me to get a medication that was designed to treat an actual illness. And they do not care. They think they are owed the side effects without ever needing the treatment. And if you dare to be upset about it, you are labeled bitter or jealous. I have fought through years of systemic discrimination. I have been laughed at. Ignored. Told to “just lose weight” as if that would magically fix my endocrine system. Now there is finally a medication that addresses the root cause. That treats the insulin resistance itself. That gives people like me a fighting chance at stability and health. And it is being ripped out of our hands for vanity. For convenience. For aesthetics. All while, the medication alone helped me shed the first 30 pounds without much help. But I have still made huge lifestyle adjustments. It is not magic. You still have to work hard. You have to hit your protein goals. You have to strength train so you do not lose too much muscle. You have to hydrate so you do not mess around and get pancreatitis. I just feel like so many people are treating this like a fast fad, like Weight Watchers back in the day, and not considering that it was meant to treat real disorders. It is not a diet program. It is medical treatment. And it deserves to be respected like one. Is this a shared experience for anyone else? Your thin friend says, “I need it, I have gained 20 pounds and I just want to shed it. Who has time for the gym?” Your newly fat friend says, “I have tried everything but I can’t lose weight, so I must need it,” meanwhile they JUST arrived at fat town. They gained relationship weight. They have never had an endocrine disorder. Never had a metabolic issue. They could easily lose the weight with the simple lifestyle changes I have struggled against my whole life. And yet they feel entitled to the very medication people like us had to fight and bleed for. Is anyone else feeling this anger too? Or am I losing my mind? submitted by /u/Personal_Nothing_351 to r/PCOS [link] [comments]
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reddit.com |
Personal_Nothing_351 |
Apr 19, 2025 |
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I’ve officially reversed my insulin resistance with diet only
Hi All. I have a success story I wanted to share here with everyone. Maybe some of it will be helpful to you. I’ve been diagnosed with PCOS for about 7 years. My weight was at 105LB & insulin resistance was good until about 3.5 years ago. I started gaining tons of weight & didn’t know why. I know my life style wasn’t ideal but it was happening too fast. I gained 35 pounds in 2 years. A year ago I decided to go back & have my PCOS get re-evaluated. For years my BC pills were enough to manage symptoms but then I had a flare up & the symptoms got worse. A year ago my insulin resistance score was extremely high & my A1C was elevated as well. My doctor told me to eat low carb. Extremely low carb with a 1200 per day calorie limit. I did that for about 6 months & lost maybe 4-6 pounds but it was extremely miserable. I couldn’t do it anymore. I gave up & started indulging in my terrible habits again. Like an addict relapsing. I was back to drinking tons of wine & eating pasta for dinner. I gained all the weight back & felt horrible again. Then I finally decided to work with a LEGIT registered dietitian. She has been extremely helpful. She had me eat a 2/1 ratio. For each 2 grams of carbs, I have to eat 1 gram of protein. Eating carbs alone was not allowed. This allows you to eat & enjoy carbs while also slowing down digestion enough to prevent blood sugar spikes. She made me stop starving myself by eating 1200 calories. She did a reverse diet & gradually increased my daily calories up to 1800. Now, I’m able to eat more & I’ve lost 5 pounds. Still losing weight slowly, but surely. The best part? I got my blood work results & my insulin resistance is gone. I’ve now successfully made sustainable changes that I can maintain without batting an eye. If you can afford it, or your insurance covers it, I highly recommend finding a decent dietitian. Some of them have masters degrees in nutrition science & they know more than any PCP or OBGYN will know about food. If you find a decent one, they can give you relevant, science backed advice that is sustainable & shame FREE. Side note: this post is not intended to demonize medications. If your doctor prescribed metformin or some other meds. Please don’t feel discouraged from taking them. Sometimes diet changes alone are not enough & that is okay. Update : lots of you were asking me to post the test results so I’m gonna write it below. March 2023 insulin, Intact, LC/MS/MS (49) C-peptide, LC/MS/MS (5.33) Insulin resistance score ( 100 ) Now in February 2024 Insulin, Intact, LC/MS/MS 9 C-peptide ( 1.44 ) Insulin resistance score ( 24 ) Insulin resistance score reference range is anything below 60 is considered “normal” Also, my testosterone levels have improved. Not sure if that’s from the diet or switching my BC pills brand. submitted by /u/fessuoyfessouy to r/PCOS [link] [comments]
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fessuoyfessouy |
Mar 6, 2024 |
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Can someone please give me an idiots guide to Insulin Resistance and weight loss please?
I have read tons of websites, books etc over the years so I understand the science but I just can’t seem to translate it into my daily life. My questions are these: •What causes the weight gain? • What dietary changes help with weight loss? • What exercises help with weight loss? • Any other advice? Thanks in advance! submitted by /u/ShihtzuMum39 to r/PCOS [link] [comments]
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ShihtzuMum39 |
Aug 30, 2022 |
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The effect of a fruit-rich diet on liver biomarkers, insulin resistance, and lipid profile in patients with non-alcoholic fatty liver disease: 6 month RCT indicated that consumption of fruits more than 4 servings/day exacerbates steatosis, dyslipidemia, and glycemic control in NAFLD patients
submitted by /u/Meatrition to r/science [link] [comments]
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reddit.com |
Meatrition |
Jul 13, 2022 |
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Exercise prevents the development of insulin resistance through the development of skeletal muscle NADPH oxidase 4 (NOX4)
submitted by /u/cestlavie_27 to r/science [link] [comments]
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reddit.com |
cestlavie_27 |
Dec 20, 2021 |
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65lbs Lost = Insulin Resistance Reversed!
23 5ft SW: 175 CW: 109.8 GW: 100 So happy because I haven’t been this small in 8 years😊 Also met my quarantine weight loss goal, wanted to be 110 by mid-July or by the time my state fully reopened. I started this journey to look and feel better but improving my health was also in the back of my mind. 5 years ago, I was diagnosed with insulin resistance and PCOS at 140lbs. I was advised to lose weight and the doctor (an endocrinologist) offered metformin and birth control to control these conditions because it would be “hard” to lose weight without medication. Personally, I felt that the doctor was a bit pushy about the medications and negative about the prospect of losing weight without going on any medications. But I decided to skip the medication because I didn’t feel it was necessary and told the doctor I would just lose weight on my own. Well I left for college a few months after that appointment and the college lifestyle (combined with me just not caring about my weight) led to me putting on 35lbs by the middle of my senior year. At my highest weight, I was likely pre-diabetic. Being alone on campus for a winter class led me to eat out of boredom and I put on a few pounds. I had also been buying whatever I wanted and it was a bunch of junk food like ice cream and cheesecake. Seeing myself in the mirror, I hated how fat I’d become and I knew I did not want to keep getting any bigger. For the first time in my life, I made a serious effort to lose weight and I’m glad I did it on my own (through college, a semester of grad school and quarantine) because it showed me that even with insulin resistance and PCOS, the weight can still come off by cooking healthier foods at home, counting calories, working out and having discipline (you won’t always feel motivated). Anything is possible when you put your mind to it. At first, my goal was to just “lose weight” because I’d never done it before. But as I started making lifestyle changes and saw the weight coming off, I started to believe I could do it. I still have PCOS and I ended up getting a hormonal IUD 3.5yrs ago to get rid of my heavy, irregular periods after I had one that that lasted for 2 months. Truly one of the best decisions I’ve ever made. However, I’m 99% sure I no longer have insulin resistance since I’m 30lbs under my diagnosis weight and my Acanthosis nigricans aka. “dark neck” cleared up somewhere between 140-150lbs, approximately 6 or 7 months into my lifestyle change. All it took was making true lifestyle changes vs trying to “diet”. Though I can’t go to an endocrinologist to take an official test right now with covid going on. Maybe it’s because I’m 5ft on top of my family history, but it doesn’t take much extra weight for me to develop insulin resistance so even though I was diagnosed at 140lbs, it is entirely possible that developed it at a smaller weight. I share all this because I see a lot of women use PCOS as a reason they “can’t” lose weight. While it can definitely make it harder to lose weight, hard ≠ impossible. Anyone will lose weight if they are in a caloric deficit. I’ve also heard of a lot of doctors being a bit eager to prescribe metformin to help with insulin resistance. There is absolutely nothing wrong with taking it but please don’t feel like metformin is necessary for weight loss if you are insulin resistant. I know someone who has been on metformin for years for their pre-diabetes. He has only kept gaining weight because he doesn’t want to commit to a lifestyle change. Metformin can absolutely help you lose weight but *only\* if you put in the work. https://imgur.com/a/b3VFlKc submitted by /u/KittyMinty to r/loseit [link] [comments]
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KittyMinty |
Jun 30, 2020 |
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Does insulin resistance make "calories in/calories out" less relevant for weight loss?
Before getting into a drawn out argument with my SO over this, I wanted to see if anyone here can point me to some facts. In my own fitness journey (currently bulking) I've come to realize wight gain/loss really is as simple as CICO. While it probably makes more sense in the long term to get your calories from a balanced diet, 100 calories of kale = 100 calories of cookies in terms of weight management. Now, my SO has some degree of insulin resistance. The diagnosis doctors have given her is PCOS but that's highly over-diagnosed and the only symptom she really has is the insulin resistance. She's small, 5'2" and 120lbs-ish, but has some stubborn subcutaneous fat on her torso, and she argues that for someone with insulin resistance it's not as easy for her to lose it, and that not every calorie is created equal. If you google "insulin resistance and weight loss" you'll see this over the over: ...insulin resistance is probably one of the biggest causes of their weight loss frustration Browsing some threads here and /r/PCOS it seems many of the women have had more success with keto/paleo/low GI diets. My inclination is to insist that if she creates a caloric deficit, the fat will come off. The blood sugar regulation part of it has more to do with curbing cravings and diet sustainability, but it does NOT mean that how she gets her calories "modifies" how fat is stored in her. Can anyone point me to some resources or shed some light? submitted by /u/banks_banks to r/Fitness [link] [comments]
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reddit.com |
banks_banks |
May 9, 2018 |
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TIL that Alzheimer's disease is considered by some scientists to be Type 3 diabetes because it results from resistance to insulin in the brain.
submitted by /u/buzznights to r/todayilearned [link] [comments]
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reddit.com |
buzznights |
Jun 16, 2016 |